The pharmaceutical giant Novartis ($NOVN (+3,13 %) ) is attracting attention with a new acquisition: the company is securing a promising cancer drug from Synnovation Therapeutics - with a total volume of up to USD 3 billion.

_________________________

💰 1. deal details

• Total volume: up to USD 3 billion
• USD 2 billion immediately
• A further USD 1 billion in milestone payments
• Acquisition will take place via the subsidiary Pikavation Therapeutics

📌 Goal: access to the drug program around SNV4818

_________________________

🧬 2. what is it specifically about?

The focus is on a new type of active ingredient:

👉 SNV4818 - a so-called PI3Kα inhibitor

• currently in phase 1/2 trials
• Use in breast cancer (HR+/HER2-) and other tumors
• specifically targets mutated cancer cells
• Should have fewer side effects than existing therapies

💡 Background:

Around 40% of breast cancer patients in this segment have corresponding mutations - a large addressable market.

_________________________

⚔️ 3. Strategic importance for Novartis

Why does Novartis pay so much money?

👉 Several reasons:

• 🛡️ Securing its own market position in the cancer field
• 📉 Impending patent expirations for existing blockbusters
• ⚔️ Increasing competition (e.g. from Roche, AstraZeneca, Eli Lilly)

👉 Particularly important:

Novartis already has a PI3K inhibitor on the market with Piqray - the new candidate could represent an improved next generation.

_________________________

🚀 4. why this approach is exciting

The big advantage of the new drug:

• Targeted effect only on mutated enzymes
• Healthy cells are largely spared
• better tolerability & combinability

➡️ This could lead in the long term to

• higher efficacy
• wider application
• better treatment results

_________________________

📊 5. significance for the stock market

💡 Bull case for Novartis ($NOVN (+3,13 %) ):

• Strengthening the oncology pipeline
• Access to next-gen cancer therapies
• Long-term sales potential through blockbuster drugs

⚠️ Risks:

• Drug still in early clinical phase
• High purchase price
• strong competition in the PI3K segment

👉 In short:

A classic big pharma move - expensive, but with potentially huge upside.

_________________________

🧠 Conclusion

Novartis is focusing on the future of cancer medicine:

• 💰 big deal (up to USD 3 billion)
• 🧬 Innovative technology
• ⚔️ Competition is increasing

Whether the investment pays off depends largely on whether SNV4818 is clinically convincing.

For investors, this remains the case:

👉 A clear strategic expansion of a core segment

_________________________

🔗 Source

Ground News: Novartis to acquire Synnovation Therapeutics' pan-mutant selective PI3K inhibitor program

Hello my dear GQ community, since dear @Tenbagger2024 somehow has problems with his company presentation post, I'm jumping in for a change 😝 so that you have something to read 😂 I hope I still reach a few of you readers 🤓

have fun 😬

Today I would like to introduce you to a company that I am sure many of you are not yet familiar with.

It is the Japanese BioTech Pharma / Tech (?) company with the name: PeptiDream $4587

PeptiDream $4587 is not a classic pharmaceutical company that only sells its own pills. It is a technology platformthat provides the "operating system" for the discovery of new active ingredients. In the world of biotechnology, PeptiDream $4587 is the undisputed king of macrocyclic peptides.

👤 Management: Visionary & Strategic

- CEO: Patrick C. Reid

- Reid is not a typical Japanese CEO, which gives the company a very international and agile culture. Under his leadership, PeptiDream has been transformed from a small university spin-off to a global player with over 120 research programs.

- Strategy: He consistently focuses on collaborations with "big pharma" (Novartis $NOVN (+3,13 %) , Eli Lilly $LLY (+8,82 %) Merck $MRK (+1,03 %) Genentech $GENETEC ) in order to shift the risk of failures in clinical trials onto the partners, while PeptiDream $4587 profits from milestone payments and license fees.

--------------------------

🔬🏭The business model: "The Discovery Powerhouse" 🎯

PeptiDream $4587 pursues a strategy of massive scaling through partnerships. Instead of investing billions in their own research and hoping for a "blockbuster", they let the giants of the industry work for them.

1-core technology PDPS: The Peptide Discovery Platform System is a kind of "Google high-speed search engine" for active ingredients. It can screen trillions (!) of different peptides in just a few weeks to find exactly the one molecule that binds to a disease target.

PDPS in detail:

Imagine you are looking for a matching key 🔑 for a very complicated lock (a protein that causes a disease). Classic pharmaceutical companies laboriously try out a few thousand keys 🔐.

- PDPS (Peptide Discovery Platform System): PeptiDream builds a "library" in a test tube trillions (10¹²) different macrocycles (ring-shaped peptides).

- The highlight: Each peptide is labeled with a DNA "barcode". When a peptide binds to the target protein, the barcode is read and the company knows immediately: "This is the active ingredient!"

- Success rate: PeptiDream $4587 states that for over 95 % of all biological objectives🎯 (targets) within just 4 weeks. This is record-breaking in the industry.

Technology licenses: Partners such as Lilly $LLY (+8,82 %) or Novartis $NOVN (+3,13 %) pay millions to be allowed to use the PDPS technology themselves.

🚀2 The growth pillar:

The "PDRadiopharma" transformation:

Through the acquisition of the radiopharmaceutical business of Fujifilm Toyama Chemical PeptiDream has $4587 vertically integrated. They now own the entire chain: from the discovery of the peptide to the production and marketing of nuclear medicine diagnostics and therapeutics in Japan.

This is currently the most exciting transformation. With the acquisition of PDRadiopharma (formerly Fujifilm $4901 (+1,21 %) ), PeptiDream is no longer just a software developer, but also a logistics giant. logistics giant in Japan.

- Why radiopharmaceuticals? These drugs decay quickly (radioactivity!). You need an extremely precise network to get them from the reactor to the patient. PeptiDream now has this infrastructure in Japan.

🔁3 The " $AMZN (+3,75 %)
Amazon model" of the pharmaceutical world

PeptiDream $4587 follows the principle of reinvestment:

They are using the stable cash flows from radiopharma sales in Japan to further automate their PDPS platform. The screening system is now largely robotized, which reduces the marginal costs per new project to almost zero.

--------------------------

🆕📰- Latest news (February/March 2026): PeptiDream $4587 has just completed the first patient dose in a Phase 2 trial for a new treatment for prostate cancer (177Lu-PSMA-I&T) in Japan. This is in collaboration with the Curium Group.

Strategic realignment 2026

The latest earnings calls (February 2026) show that

- Focus on in-house development: PeptiDream is moving to bring more programs to clinical phase 1 or 2 itself before licensing them. Although this will increase costs in the short term (R&D budget for 2026 increased to approx. JPY 6.4 billion), but massively increases the value of the deals.

- Pipeline turbo: The number of clinical programs (the phase where it gets really expensive and valuable) has almost doubled in the last year. The target for T2026 is 6 to 12 new clinical programs

--------------------------

🤝The "Big Three" alliances

These are the most lucrative and strategically important partnerships, often worth billions (in milestones).

- Novartis $NOVN (+3,13 %)
: Probably the closest partner. In May 2024 the collaboration was massively expanded. Novartis paid USD 180 million in advancewith the prospect of a total of up to USD 2.71 billion. Focus: Radioligand therapy (RLT). Novartis uses PeptiDreams peptides to precisely steer radioactive particles to tumors.

- Eli Lilly $LLY (+8,82 %) A partnership worth up to 1.2 billion USD. Lilly is using the PDPS platform primarily to find peptides that can deliver drugs across the blood-brain barrier or for the next generation of metabolic drugs (keyword: weight loss injection optimization).

- Bristol Myers Squibb $BMY (+3,5 %): BMS has "inherited" an existing alliance with PeptiDream through the acquisition of RayzeBio. This is also about targeted cancer therapy.

The global network (excerpt)

In addition to those mentioned above, there are over 120 research programs. The partners include:

- Merck (MSD) $MRK (+1,03 %)
: Focus on various therapeutic areas.

- Genentech (Roche): $ROG (+1,61 %) Collaboration on multi-specific antibodies and PDCs.

- Astellas $4503 (+0 %)
& Takeda $4502 (+2,47 %) Strong local partnerships in Japan.

- Amgen $AMGN (+0,38 %)
& Bayer $BAYN (+4,94 %)
: Licensees of the PDPS technology.

--------------------------

📊Sales development (growth leap through acquisition) in recent years:

- 2021: approx. JPY 9.4 billion

- 2022: approx. JPY 26.8 bn (massive leap due to the integration of the Fujifilm radiopharmaceuticals business)

- 2023: approx. JPY 31.1 bn

- Trend: Sales have more than tripled within three years. While milestone payments used to account for almost 100% of revenue, stable revenue is now generated from the sale of radiopharmaceutical diagnostics in Japan.

📈Profitability and margins

PeptiDream $4587 is an exception in the biotech sector, as they have been almost consistently profitable:

- Operating margin: This often used to be over 40-50% (before 2022) as there were hardly any production costs. Since the acquisition of the radiopharmaceutical business, the operating margin has fallen to around 20-25 % has fallen. This sounds like a step backwards, but it is a sign of a more mature business model with physical products.

- Net result: After a dip in 2022 (acquisition costs), net profit stabilized significantly in 2023 and 2024. For 2025/26 the economies of scale of the PDPS platform are expected to lead to rising margins again.

Expenditure on research and development

A critical point for biotech:

- PeptiDream $4587 continuously spends about 20-30 % of its turnover on R&D.

- The special feature: Since partners (such as Eli Lilly $LLY (+8,82 %) or Novartis $NOVN (+3,13 %) ) pay for phase 2 and 3 clinical trials for the joint programs, PeptiDream's burn rate remains extremely low compared to US biotechs. $4587 remains extremely low compared to US biotechs. They conduct research "at the expense of others".

💴The cash position and debt:

- Cash reserves: At the end of 2023/beginning of 2024, the company held approx. JPY 28-30 billion in cash and cash equivalents.

- Debt: Debt was raised through the acquisition of PDRadiopharma, but the ratio of net debt to EBITDA is very healthy (often below 1.0), which means a very conservative balance sheet for a growth company.

The "pipeline" key figures

The most important non-financial key figure for PeptiDream $4587 is the number of programs:

- 2020: approx. 100 programs

- 2024: over 120 programs️

- Meaning: Each program is a "ticket" in a lottery in which PeptiDream $4587 does not pay for the stake, but participates in the winnings. According to management, the hit rate of PDPS technology in identifying binding agents is almost 100%.

The current key figures 2025/26 📊

- Market capitalization: approx. USD 2.5 - 3 billion (depending on exchange rate).

- Exchange rate: approx. 2,200 - 2,500 JPY (TSE: 4587).

- Sales forecast 2026: approx. 32 billion JPY.

- Profitability: PeptiDream $4587 is one of the few biotech companies that has been consistently profitable for years.

- Growth turbo: For 2026, profit growth of over 30 % driven by new clinical programs (target: 6-12 new programs in 2026).

- Return on equity (ROE): Forecast at approx. 17 %which is exceptionally efficient for the biotech sector.

Key figures for the last few years:

The market often punished the share between 2021 and 2023 because the integration of the radiopharmaceuticals division diluted the clean "software margins".

Since 2024, however, the market has recognized the strategic value 👀:

PeptiDream $4587 is now no longer just a supplier of ideas, but controls the platform and the delivery (PDCs).

--------------------------

Why is the share exciting? (Bull case) 🚀

1. Validation by giants: When companies like Eli Lilly $LLY (+8,82 %) (market leader in weight loss products) sign contracts worth USD 1.2 billion with PeptiDream $4587 shows the quality of the technology.

2. Scalability: PeptiDream $4587 can earn money on hundreds of drugs simultaneously without bearing the full development costs.

3. Radiopharma boom: The market for targeted radiation therapy (radioligand therapy) is exploding right now. PeptiDream $4587 is perfectly positioned here thanks to PDRadiopharma and the $NOVN (+3,13 %) Novartis deals perfectly positioned.

4. Enormous upside potential: Many analysts see a price target of over JPY 3,000which corresponds to a potential of +30 % to +50 %.

Risks (bear case) ⚠️

- Dependence on partners: If a major partner stops a program, planned milestone payments are lost.

- Currency risk: As many contracts are in USD but invoiced in JPY, exchange rate fluctuations affect the balance sheet.

- Clinical setbacks: Despite the best technology, drugs can fail in phase 2 or 3 due to side effects.

--------------------------

✍️Meine personal conclusion & rating:

At first glance $4587 an absolute disaster in terms of share price and key figures, but Peptidream $4587 is the "paddlewheel stock" in the gold rush of modern drug discovery. If you don't want to bet on a single drug, but on the technology that makes them all possible, you will find a highly profitable niche king here. The potential is definitely there.

- Status: Growth stock with solid cash position (approx. JPY 28 bn reserves).

- They do not develop drugs, but the "peptide keys" that bring active ingredients precisely into the cell. In 2026, their radiopharma division will be the big driver.

- Status: Platform model with many global partners (license fees)

-The big $LLY (+8,82 %) & $NOVN (+3,13 %) - effect

unfortunately the share is not (yet) tradable in Germany only on the Tokyo Stock Exchange 🥲

Your stock master ✌️

Looking forward to your assessment of how you rate the company?

@Tenbagger2024
@Get_Rich_or_Die_Tryin
@PikaPika0105
@Multibagger
@Klein-Anleger
@Raketentoni
@Liebesspieler
@HoldTheMike
@Shiya and of course others from the community 🙇‍♂️

Novo Nordisk 3.0% $NOVO B (+4,52 %) NVO

LVMH 2.0% $LVMH

Pernod Ricard 6.35% $RI (+0,37 %)

Imperial Brands 5.5% $IMB (+1,84 %)

BAT 6.2% $BATS (+1,83 %)

Sunrise Communications 8.00%

Nestle 4.05% $NESN (+0,95 %)

Roche 2.85% $ROG (+1,61 %)

Novartis 3.07% $NOVN (+3,13 %)

Shell 4.07% $SHEL (+1,82 %)

German Post 3.86% $DHL (+8,23 %)

Swisscom 3.75% $SCMN (+2,88 %)

German Telekom 3.52% $DTE (+1,32 %)

Strabag 2.72% $STR (+1,36 %)

Vonovia 4.82% $VNA (+1,35 %)

BASF 5.01% $BAS (+1,61 %)

Puma 2.8% $PUMA

Hannover Re 3.62% $HNR1 (+1,17 %)

Munich Re 3.8% $MUV2 (-3,1 %)

Allianz 4.00% $ALV (+1,12 %)

BP 5.76% $BP. (+1,2 %)

Spotify

https://open.spotify.com/episode/1zt05UZlehInr81iaZMdY5?si=e676f0a812014943

YouTube

https://youtu.be/BpCIIJYfxHA

Appple Podcast

https://podcasts.apple.com/de/podcast/125-20-europ%C3%A4ische-dividenden-aktien/id1695869891?i=1000744769342

Following the rebalancing of the S&P Quality Aristocrats last Friday, the following stocks were removed from or added to my two ETF indices (50% weighting):

New additions:

$QDEV (+0,38 %): $NOVN (+3,13 %) , $REL (+1,11 %) , $ITX (+0,24 %) , $LSEG (-0,18 %) , $DB1 (-0,85 %) and more

$QUS5 (+0,35 %): $BKNG (-2,99 %) , $MRK (+1,03 %) , $CRM (+0,33 %) , $UNP (+0,64 %) , $COR (-1,57 %) , $CAH (-5,15 %) and more

Kicked out of both indices and therefore according to S&P no longer Quality Aristocrats are among others: $BATS (+1,83 %) , $7974 (-0,21 %) , $HD (+1,56 %) , $LOW (+1,93 %) , $HLT (+2,38 %)

In addition, the allocation of all individual stocks in the indices was reduced again to max. 5 % was limited.

Thanks to the recent rally of $$HY9H (+0,4 %) my current top 10 weighting (ETFs+shares) is as follows:

3.48% Alphabet

3.04% SK Hynix

3.04% Broadcom

2.93% Meta

2.75% Microsoft

2.71% Apple

2.71% NVIDIA

2.55% Taiwan Semiconductor

2.13% Mastercard

2.08% Visa

New portfolio key figures:

P/E: 27.1 (<30) 🟢

Forward P/E: 21.1 (<25) 🟢

P/Β: 11.5 (<5) 🔴

EV/FCF: 28.7 (<25) 🟡

ROE: 42% (>15%) 🟢

ROIC: 19% (>15%) 🟡

EPS growth for the next 5 years: 15% (>7%) 🟢

Sales growth for the next 5 years: 9% (>5%) 🟡

My internal rate of return is currently 20.19%

Even in uncertain times like these, there are reliable stocks: with strong growth and stable dividends. Here are the best stocks from the Stoxx Global 1800.

Excluded were:

1. liabilities/total capital > 70%

2. negative EPS development in the last 5 years and those where analysts see a negative development in the next few years

3. KCV > 20

4. p/e/earnings growth > 5

5. companies that have canceled or cut dividends in the last 25 years

I'll name a few of the remaining companies here and maybe there are some that you don't know yet. Of course, these include companies such as Caterpillar, Chevron, Henkel, Munich Re, Merck and Union Pacific. They are well known. The following stocks are stable, established companies, so please don't expect any tenbagger opportunities in the next 10 months ;)

Armaments:

BAE Systems $BA. (+2,33 %)

If Europe wants to build a missile defense shield, there is no way around BAE Systems: the British armaments group was formed 26 years ago from the merger of British Aerospace and telecommunications supplier Marconi. BAE is building the Eurofighter Typhoon fighter aircraft with Airbus, and the company is also developing a new nuclear submarine for the Royal Navy. Since Russia's attack on Ukraine, the British company's order backlog has been growing and CEO Woodburn has raised the profit outlook for this year.

General Dynamics $GD (+1,17 %)

The German Armed Forces are receiving new ambulances: 80 so-called Eagle V 6x6s from the US armaments company General Dynamics. However, the Virginia-based company is best known for its Fighting Falcon F-16 fighter aircraft, which was launched in 1978 and is one of the most widely used military jets in the world. However, the fact that General Dynamics has recently surprised with positive sales and profit figures is due to its submarine division: the US Department of Defense significantly increased an existing order.

Construction

Ackermans & van Haaren $ACKB (+2,33 %)

The deepening of the Elbe near Hamburg is controversial, but the marine technology company Deme, the highest-revenue subsidiary of the Belgian conglomerate Ackermans & van Haaren, continues to dig. Deme is also involved in the construction of offshore wind farms and gas pipelines. Ackermans & van Haaren is also active in banking and the energy sector. The company's coffers are well filled and the profit prospects are intact.

Assa Abloy $ASSA B (+2,31 %)

If you have never heard of Assa Abloy, you should look out for the manufacturer of security doors. It often bears the name of the Swedish company, which claims to be the world market leader for security and access systems. Assa Abloy regularly strengthens its position with acquisitions - twelve in the past few years. The Group can afford this, as can the rising dividend.

Idex $IEX (-0,24 %)

Without water pumps from Godiva, many firefighters would quickly be left high and dry. The pumps from the US company Idex are installed in fire engines worldwide, but also in aircraft, for example. With the purchase of Micro-Lam, Idex is strengthening its optical systems division in order to win the defense industry as a customer. The share has recently been under pressure.

Pharmaceuticals

Novartis $NOVN (+3,13 %)

At the beginning of September, things went from strength to strength at the Swiss pharmaceutical group: first the healthcare giant from Basel secured the worldwide license for a new Parkinson's drug, then access to several new cardiovascular drugs from China. Both therapies have the potential to generate billions in sales in the near future. Novartis can also be satisfied with its own developments: according to initial studies, the Swiss company is on the trail of an active ingredient that should help against Sjögren's syndrome, a common rheumatic disease. But Novartis is also under the threat of US tariffs. Novartis generates around 40 percent of its total sales, approximately 17 billion euros, in the USA. To avoid the additional burden, the company is investing in seven new production facilities there.

Industry

Kurita Water $6370 (+2,01 %)

The fact that astronauts on the ISS space station have clean water is mainly thanks to the Japanese company Kurita Water. The company specializes in water treatment, develops systems and chemicals for this purpose and uses them to build self-sufficient water systems - a business with good prospects. Kurita Water also scores with stable finances and a rising dividend.

SGH $SGH (+2,16 %)

Under the umbrella of the Australian conglomerate SGH (formerly Seven Group Holdings), there is a strange mix: on the one hand, SGH sells construction machinery, building materials and energy. On the other hand, the Chairman of the Supervisory Board, Kerry Stokes, is something of a second Rupert Murdoch thanks to his shares in the media group Seven West Media. SGH has doubled both its profit and turnover since 2020.

Spirax $SPX (+0,91 %)

The highly upgraded steam systems from Spirax (formerly Spirax-Sarco) are used in almost all industries and sectors. However, the most promising segment is "electrical heating solutions". Here, Spirax is developing CO2-free systems for gas-powered steam power plants, for example. Spurred on by the business prospects, the share price jumped - but the price is still below the value targeted by analysts.

Source: Capital Magazine

📈 New purchase - CapsoVision

I am with CapsoVision
$CV an innovative MedTech company that is setting new standards with its 360° capsule endoscopy. No external recorder required, full perspective - and already FDA-approved & in use in the USA.

💡 Why this investment?

• Technological advantage compared to traditional solutions (e.g. PillCam from Medtronic)
• Already cooperating with Pentax Medical
• Focus on early detection & diagnosticsa megatrend in the healthcare sector
• Low market capitalization (~180m USD) with a lot of upside potential

🚀 Vision:

If CapsoVision reaches USD 50-100m sales in the medium term, a multiple in the share price is possible. In the long term I see 10-25 USD+ per share as realistic - depending on market penetration and access to capital, of course.

I think: exciting small cap story with disruptive potential - What do you think?

👉 Do you know the company? How do you rate the opportunities & risks?

Please leave your opinion!

#aktien
#investieren
#MedTech
#CapsoVision
#SmallCap
#langfristig
#innovation
#getquin
#medizin
#medizintechnik
#pharma
#medical
#zukunft
$NOVO B (+4,52 %)
$PLTR (+2,45 %)
$AMD (+5,54 %)
$NOVN (+3,13 %)

$NOVN (+3,13 %)

• New study data show a significantly improved efficacy of the cancer drug Kisqaliespecially in women under 40 years of age.
• The combination with endocrine therapy significantly delays the course of the disease.
• This makes Kisqali more attractive for a broader application and could against competing drugs.
• The data were presented at a leading oncology conference and could Strengthen Novartis' market position.

Source: https://de.investing.com/news/economy-news/novartisbrustkrebsmittel-kisqali-ist-auch-bei-jungeren-patientinnen-wirksam-3019861

Since the beginning of the year, analysts have lowered their profit estimates for the 50 largest listed companies in Europe by almost four percent. This is according to data from the financial specialist Bloomberg.

One of the main reasons for this is the tariffs imposed by US President Donald Trump Trump and the associated uncertainty. Tariffs make products more expensive, making them less affordable for end customers. In addition, the recent euro exchange rate against the dollar is affecting companies. This makes products sold in the dollar zone more expensive and less competitive. In addition, turnover and profits are reduced as soon as companies convert their dollar earnings into euros and report them on their balance sheets.

But there are exceptions. For five companies in the European Stoxx 50 share index, analysts have increased their profit forecasts for the current financial year by at least five percent since the beginning of the year. by at least five percent - for one group by as much as 15 percent.

Handelsblatt profiles the shares of these companies with a view to their business prospects, their stock market valuation and their share price potential.

The candidates are:

$PRX (+1,47 %) - Prosus | 20 analysts per buy / 4 hold

$CFR (+3,34 %) - Richemont | 17 buy / 16 hold / 1 sell

$NOVN (+3,13 %) - Novartis | 9 buy / 15 hold / 5 sell

$SAP (-0,91 %) - SAP | 25 buy / 6 hold / 3 sell

$IBE (+0,68 %) - Iberdrola | 12 buy / 19 hold / 2 sell

The detailed analysis is available here (€):

https://hbapp.handelsblatt.com/cmsid/100124777.html

Source: Handelsblatt, 09.05.25

Lufthansa: $LHA (+3,64 %)

- Q1 revenue: €8.13bn (expected: €8.04bn)

- Q1 adj. EBIT: € -722 million (expected: € -718 million)

- Passenger airlines weaker than expected.

- Forecast 2025 confirmed: Significantly higher adj. EBIT than 2024.

- Task force for rapid capacity adjustment in the event of weaker demand.

- North American traffic strong in Q1 (+25% US passengers in March).

HelloFresh: $HFG (+3,36 %)

- Q1 revenue: € 1.93 billion (-7%), adjusted EBITDA: € 58.1 million (+250%).

- Efficiency program bears fruit.

- 2025 forecast confirmed: Sales -3% to -8%, EBITDA € 450-500 million.

Novartis: $NOVN (+3,13 %)

- Q1 net profit: USD 3.6 bn (+33%).

- Forecast raised: Sales growth now expected in the high single-digit percentage range.

Mutares: $MUX (-0,7 %)

- Q1 revenue: €1.53bn (+13%), net result holding company: €29.5m.

- Exits planned for 2025 (>€200m gross proceeds expected).

- Partial sale of Steyr Motors generates € 74m.

Symrise: $SY1 (-0,54 %)

- Q1 organic growth: 4.2%, sales: € 1.32 bn.

- Full-year forecast confirmed: 5-7% organic growth, EBITDA margin ~21%.

DWS Group: $DWS (+1,07 %)

- Q1 revenues: €753m (+3%), net income: €199m (+13%).

- Record inflows: € 19.9 billion.

- Cooperation with Deutsche Bank in the Private Credit segment.

Deutsche Bank: $DBK (+0,73 %)

- Q1 pre-tax profit +39%, highest quarterly profit in 14 years.

- Revenue growth and cost reductions drive earnings above expectations.

Johnson & Johnson (Pharmaceuticals) - $JNJ (+0,65 %) Invests over 55 billion US$ in the USA within four years to expand production and researchreuters.com. Four new plants are planned (the first in Wilson, North Carolina, has already been launched)reuters.com. This step was taken in March 2025, shortly after the Trump administration imposed a import tariff of 25 % on medicines on medicines and is intended to help produce more medicines domesticallyreuters.com
reuters.com. (Source: company statement/Reuters)

Roche (Pharmaceuticals) - $ROG (+1,61 %) The Swiss pharmaceutical company announced 50 billion US$ investments in the USA over the next five yearsfaz.net. This is Roche's response to President Trump's threat to impose tariffs of ~25 % on pharmaceutical importsto produce more important medicines in the USAfaz.net
faz.net. Plans include 1,000 new jobs in production and research (plus approx. 11,000 jobs with suppliers and construction) in the USAfaz.net. Announcement was made in April 2025 (Source: Company statement/F.A.Z.)

Eli Lilly (Pharma) - $LLY (+8,82 %) Announced in Feb. 2025, 27 billion US$ to invest in the construction of four new production facilities in the USAreuters.com. This is expected to more than double US production capacity and create over 3,000 new high-tech jobs (plus ~10,000 construction jobs)reuters.com. The background to this is the threat of a 25% tariff on drug imports, which is prompting Lilly to relocate production from Ireland & Co. to the USAfaz.net. (Source: Company statement/Reuters)

Novartis (Pharma) - $NOVN (+3,13 %) Plant 23 billion US$ for the expansion of 10 US sites (including 6 new production plants and an R&D center in San Diego)reuters.com. This five-year investment offensive (announced on April 10, 2025) comes two days after Trump announced "big tariffs" on drug imports
reuters.com. Novartis wants to relocate the production of important drugs to the USA (>1,000 new highly qualified jobs plus ~4,000 jobs in construction and support)reuters.com
reuters.com. (Source: Company statement/Reuters)

Merck & Co (Pharmaceuticals) - $MRK (+1,03 %) In March 2025, the US pharmaceutical company (not to be confused with Merck KGaA) opened a new US$ 1 billion plant in North Carolina and announced plans to invest a total of ~8 billion US$ in the USA by 2028reuters.com
reuters.com. Trump is increasing the pressure on the industry to move production back and has threatened to impose 25 % tariffs on pharmaceutical products
reuters.com. Merck has responded by investing over USD 12 billion in US plants since 2018 and is continuing to expand in order to circumvent import tariffsreuters.com
reuters.com. (Source: Reuters)

Hyundai (Automotive) -$HYUD In March 2025, the South Korean manufacturer announced a package of 21 billion US$ of investments in the USAspectrumlocalnews.com. This includes, among other things US$ 5.8 billion for a new steel mill in Louisiana (approx. 1,400 jobs)spectrumlocalnews.com and a new e-car plant in Georgia (US$ 8 billion)which will create over 8,500 jobsspectrumlocalnews.com. Hyundai is thus increasing its US production capacity to over 1 million vehicles/year
autohaus.de
spectrumlocalnews.com. President Trump saw this as a success for his tariffs - Hyundai would "produce its steel in America and build cars in America and therefore not have to pay tariffs"
autohaus.de
spectrumlocalnews.com. (Source: Company statement/Spectrum News)

Stellantis (Automotive) - $STLAM (-5,88 %) The Fiat-Chrysler/PSA Group provides 5 billion US$ to expand its US production facilitieswhitehouse.gov. The centerpiece is the reopening of the Belvidere plant (Illinois), which was shut down in 2023 to produce new models (including a mid-size pickup)automotivemanufacturingsolutions.com. This will create around 1,500 jobs for regular UAW employees will be restoredautomotivemanufacturingsolutions.com
automotivemanufacturingsolutions.com. This investment was announced in late 2024/early 2025 in connection with the new UAW collective bargaining agreement and Trump's auto tariffs (25% on imported cars from April 2025) agreed - Stellantis' Chairman met personally with Trump to "secure the future of the company"automotivemanufacturingsolutions.com. (Source: Company statement/FT/AMS)

TSMC (Semiconductor) - $TSM (+0,83 %) The Taiwanese chip contract manufacturer TSMC announced in March 2025 that it will invest an additional 100 billion US$ to invest in the USAreuters.com. The plan is to build five new factories over the next few years (three chip fabs, two packaging plants and a large R&D center)reuters.com
reuters.com. The background to this is US efforts to be less dependent on Asian chips (national security) - Trump emphasized that key semiconductors "be built here in the USA"reuters.com. TSMC's expansion is expected to create 40,000 construction jobs in four yearsreuters.com and reduce dependence on imports. (Source: Company statement/Reuters)

Apple (Electronics) - $AAPL (-0,38 %) The tech company announced 2025, 500 billion US$ to invest in US manufacturing and educationwhitehouse.gov. This enormous sum (over 4 years) includes already planned expenditures, but signals Apple's willingness, to relocate more production and value creation to the USA
reuters.com. Apple has been under pressure because many of its products (iPhone, Mac) are manufactured in China and are targeted by Trump's China tariffs could be targeted by Trump's China tariffs. The investment pledge - including new US locations and supplier programs - is intended to help maintain exemptions from import tariffs and promote "Made in USA"reuters.com
reuters.com. (Source: Company statement/White House, Reuters)

Sources: Primary data from the companies and reports (F.A.Z., Reuters, Spectrum News, etc.), see citations.