Hi everyone, I'm rebalancing my portfolio and adding new assets. Is this a good strategy for a medium- to long-term investment? The goal is to generate returns without compromising too much on capital preservation.

Any suggestions?

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$Salesforce

$BTEC (-2,3 %) iShares US Nasdaq Biotechnology

The ETF has gained 25.8% since April 8.

Momentum is high, valuations have been very low for a long time.

Pipeline: In recent months, major companies have announced major successes in trials, especially in autoimmune diseases, oncology and genetic medicine.

Innovation: Technological progress is also being made with AI-supported molecular research, mRNA technologies and cell-based therapies.

Takeovers: Big Pharma is investing and wants to secure future technologies, expand its pipeline and close revenue gaps following patent expiries

Capital flows: This has restored the confidence of institutional investors in particular.

In Q3 2025, these inflows were at a three-year high, particularly from funds from the US and Scandinavia.

Source: boerse-inside.de

I have personally noticed that people like Stanley Druckenmiller have had large biotech holdings recently. Steve Cohen also has a few biotech stocks as his largest position after the usual tech companies.

I think the momentum will continue for some time and it's not just hype but substance.

Thinning portfolio is placed in $SPYD (+0,48 %) is put into

What is the best way to get off here? 😭😭😭 $2B70 (-2,3 %)

I think that in an inflationary environment and an environment with rising key interest rates, healthcare & pharma & biotech will outperform. Many stocks are so cheaply valued that the upside is simply much greater than the downside. Wall Street is underinvested in healthcare.

However, when looking for a meaningful ETF on this, I run into difficulties. Practically all ETFs in the sector available in Germany have United Health, Pfizer, Lilly, etc. as their largest position. They are all strongly run and no longer really cheap. That's why I don't really think the healthcare ETFs make sense, because I'm not taking advantage of the undervaluation.

The only ETF that comes close to my criterion is this one. It holds (weighting sorted in descending order):

-Amgen

-Gilead

-Moderna

-Regeneron

-Illumina

-Vertex

-Biogen

-Astra Zeneca

-Seagen

-Biontech

Of these, at least half of the largest stocks are promising and favorable. But unfortunately it is still not optimal. I would love to put together my own ETF as I do with the Semis, but unfortunately I lack the capital lmao.

What are the opinions here? Do you have interesting alternatives?

Would you recommend this ETF?

The goal is to build something in the long term and I think in an ETF is not wrong before you get many individual stocks separately.

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