Sanofi Pastr

Acambis plc is a biopharmaceutical company operating in the infectious disease arena, with a focus on developing new vaccines. The Company supplied smallpox vaccines to more governments than any other company. To maximize the revenues from its smallpox franchise, the Company is now targeting two principal opportunities: ACAM2000 warm-base manufacturing for the United States Government and supply of MVA3000 to the United States Government. Warm-base manufacturing would produce doses of ACAM2000 each year for the Strategic National Stockpile. Together with its partner, Baxter International Inc., the Company is bidding for a major contract to supply the United States Government with doses of its MVA3000 attenuated smallpox vaccine. This vaccine is for the proportion of the population who could suffer adverse reactions to smallpox vaccines, such as ACAM2000. On September 25, 2008, Sanofi Pasteur Holding SA completed the acquisition of Acambis plc.