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+++ Oral Wegovy is not the solution for Novo Nordisk +++

The recent development of $NOVO B (+3,27%) around the oral Wegovy appears to promote growth at first glance, but on closer inspection turns out to be a clear burden on profitability.


Due to the very low bioavailability of an orally ingested peptide, around 70 times more active ingredient has to be used compared to injections. At the same time, prices for Wegovy have fallen significantly, leading to sharply rising production costs and falling revenue per patient and putting margins under considerable pressure.

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This means that sales do not necessarily increase, as the margins reduce this effect. In addition, the advantage is only there as long as Lilly does not launch a product on the market. In addition, this leads to lower margins in the entire pipeline.


Competitive pressure further exacerbates the situation. $LLY (-0,3%) Lilly is about to enter the market with an oral GLP-1 product on a small molecule basis, which is structurally cheaper to manufacture and puts Novo at a long-term disadvantage in terms of both price and margins. Despite potential sales growth, this threatens a sustained deterioration in earnings quality.


As a result, Novo still remains a risk area for me: value is not yet being generated here and the risk/reward profile does not fit for me!


The future will show: Will NOVO get 3x more customers as a result of the price cut? Then the price cut will have paid off and sales will remain the same. Has the barrier to trying Wegovy through oral pills fallen? (YES) But as I said, this can take time and initially weigh on sales!


My motto: Wait and see how it establishes itself, you may lose a return of 20% but you have certainty!

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9 Commenti

immagine del profilo
Thank you for your perspective. I got in some time ago at just under €40 and am curious to see what the future holds. Best wishes and happy new year 🎉
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immagine del profilo
@Chriscoin87 thank you also a happy new year
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immagine del profilo
Well, $NOVO B should not be reduced to weight loss stories alone. Novo Nordisk is well positioned in the market for synthetic U100 insulins - every type 1 diabetic should be familiar with Novorapid or FIASP. Think wide :-)
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immagine del profilo
I can see sales of weight loss injections collapsing in the USA from January. Who is going to buy the syringes for 349 dollars when they can buy a month's worth of tablets for 149 dollars! Novo Nordisk will clearly dominate the weight loss market in the USA from January, as the competitor product will only be available months later and is likely to be significantly less effective, I'm not worried about Novo's share price over the next few months - it should be fine.
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immagine del profilo
@Matzke That's too easy to say. The customer gain does not compensate for the loss of margin, the first effect is negative in the long term, this can change through retention
immagine del profilo
@Aktienfox Novo Nordisk has to sell 2.6 times as many pills. Pills are much more scalable than syringes - pills last longer, do not need to be refrigerated, the syringes themselves are not needed. The pills are by far more suitable for the masses than syringes. The pills will establish themselves as a lifestyle product - the prescription is just a formal act. The pills are a simple, affordable solution for anyone with a few kilos too many.
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Question: where did you get the data for the "drug cost"? Furthermore, with drug cost it is misleading if you only look at the API (active pharmaceutical ingredient) price. You still have to produce a drug from the API, and that also costs money. I don't know what the situation is here. It's as if you were looking at the price of a Golf and the cost of the steel that you install. Also, you have to look at how many customers you have. If you only sell the syringe once and the pill three times in the same time, then the figures look different.
immagine del profilo
@Spinat the active ingredient price should show the direct comparison based on the dose. The direct effect of the increase in customers will be neutral, the question is whether this can be extended to other products
To be honest, I don't know what proportion the API of finished products makes up in the price. It may be that it can be neglected.
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