Whats wrong with

Chris · 2025-04-25T17:07:15.458098Z

$BNTX go. -20% is a lot in 2 hours. Have research results been leaked?

1J

There's the reason:

Summit Therapeutics' shares plummeted on Friday. The reason for this was a report by the specialist portal Stat News, according to which the survival data from an ongoing study on the experimental lung cancer drug Ivonescimab failed to meet expectations. BioNTech shares also crashed, as the Mainz-based company is working on a similar cancer immunotherapy.

Specifically, it concerns an interim analysis of the study: after the death of 157 patients, it was shown that Ivonescimab only reduced the risk of death by around 22 percent - with a hazard ratio of 0.784. The hazard ratio is a statistical parameter that indicates how much a drug reduces the risk of a certain event - in this case death - compared to the control group.

A value of 1.0 means: no difference between the groups.

A value of less than 1.0 indicates: the risk is lower with treatment.

The closer to 0, the better the effectiveness.

The cancer drug has therefore not had the desired impact and has also fallen well short of analysts' expectations: Truist expert Asthika Goonewardene had set a ratio of less than 0.7 in his baseline estimate at the beginning of April. A ratio of 0.8 was considered his worst-case scenario.

Summit Therapeutics shares plummeted by almost 40 percent on Friday and were even suspended from trading. BioNTech shares were also hit hard, falling by more than 20 percent. The reason: BioNTech's active ingredient Gotistobart is comparable to Ivonescimab, threatening similarly poor results.

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Soprano@Soprano

1J

I don't wish any price losses on anyone, but quite honestly, anyone who invests in this scam hut is also really keen on a red portfolio.

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TomTurboInvest@TomTurboInvest

1J

@Soprano I'll look into that again in a moment. Why are you always so emotional about BionTech 😂
Didn't want to get vaccinated or why does every BionTech post trigger you so much?

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bull_investor_979@bull_investor_979

1J

@Soprano haha but really. Please stop making such dubious comments

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Chris@Multibagger

1J

@Soprano ah, I have them in a savings plan and have a purchase price of € 94. I am convinced of the value in the long term.

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Soprano@Soprano

1J

@TomTurboInvest Oh, I don't know why I'm always so upset about them. Probably because several things come together that I don't like: Lobbyism and castles in the air. There are also various other companies that I repeatedly get upset about, such as Nestle, BP, Electronic Arts, Meta, Altria, but I can always pull myself together without commenting because at least they're not hyped by anyone.

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TomTurboInvest@TomTurboInvest

1J

@Soprano Well, everyone has their own Triggerpunkte🤷🏽‍♂️
They can be a hindrance on the stock market, both positively and negatively. They can make you hang on too long to a stock that's been a pipe dream or prevent you from seizing mega opportunities.

If you have the time and inclination, take a look at the company presentation https://investors.biontech.de/de/static-files/62c14388-f316-4112-857e-4ebb34e6d3a3

The strategic acquisition of InstaDeep, the cooperation with Duality Bio in China, etc.
The cash position of over 17 billion, for me these are all tempting points that (could) lead to success in the medium term.

I also have some bad positions in my portfolio😅

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